The bacteriostatic activity of essential oils for some specimen Millefolium Koch. genus Achillea L.

Authors

  • G. P. Smoilovskaya
  • A. V. Mazulin
  • O. M. Svetashov

DOI:

https://doi.org/10.14739/2409-2932.2014.3.32852

Keywords:

Achillea, Bacteriostatic Activity, Essential Oils, Gas Сhromatography-mass Spectrometry

Abstract

Pharmacologic effect of herbal drugs is associated with the availability in its composition the complex of biologically active substances, particularly, the essential oils, which are capable to suppress the multiplication of many microorganisms, fungi, viruses.

Aim. To determine the bacteriostatic activity of essential oils of Millefolium subvulgare and Millefolium setaceum have been studied physic – chemical characters, identification and quantitative content of constituents of the essential oils obtained has been carried out by gas chromatography mass-spectrometry.

Methods and results. It has been identified in the composition of the essential oil from Achillea setacea Waldst. et Kit 63 substances, 57 substances for Achillea submillefolium Klok. et Krytzka, azulene derivatives were predominant. The subsequent bacteriostatic studies for essential oils revealed their pronounced bacteriostatic activity for Staphylococcus aureus, mixt- flore1, Pseudomonas aeruginosa, Streptococcus pyogenes, Escherichia coli.

Conclusion. The essential oil from Millefolium subvulgare demonstrated the more intensive activity associated with the predominance of azulene derivatives. 

References

(2001) Derzhavna Farmakopeia Ukrainy [State Pharmacopoeia of Ukraine]. Kharkiv: RIREKH [in Ukrainian].

(2004) Derzhavna Farmakopeia Ukrainy. Dopovnennia 1 [State Pharmacopoeia of Ukraine. Addition 1]. Kharkiv: RIREKH [in Ukrainian].

(2008) Derzhavna Farmakopeia Ukrainy. Dopovnennia 2 [State Pharmacopoeia of Ukraine. Addition 2]. Kharkiv: Derzhavne pidpryiemstvo “Naukovo-ekspertnyi tsentr” [in Ukrainian].

Kruglov, D. S., Khanina, М. А., & Tretiakova, О. V. (2006). Issledovanie specificheskoj aktivnosti nekotorykh rastitelnykh e`kstraktov [Research of specific activity of some vegetative extracts]. Uspekhi sovremennogo estestvoznaniya, 5, 50–51 [in Russian].

Kumysheva, L. A. (2009). Protivovospalitelnaia i antibakterialnaia aktivnost nekotorykh lekarstvennykh rastenii i ikh sborov – perspektivnykh mukozoprotektorov [Anti-inflammatory and antimicrobial activity of some medicinal plants and infusions as prospective mucosoprotectors]. Rastitelnye resursy, 1, 126–137 [in Russian].

Karpishhenko, A. I. (Eds.) (2002). Medicinskie laboratornye tekhnologii [Medical Laboratory Technology] Saint Petersburg: Intermedika [in Russian].

Mohyrova, L. A. (2004). Poshuk novykh biolohichno aktyvnykh rechovyn roslynnoho pokhodzhennia z antymicrobnoiu diieiu [Search for new biologically active substances from medicinal plants with antimicrobial effect]. Farmatsevtychnyi zhurnal, 3, 61–70 [in Ukrainian].

Sytnik, K. V., Androshhuk, A. F., Klokov, M. V. Krickaia, L. I., Lebedeva, T. S., Ziman, S. N., et al. (1984). Tysyachelistniki [Yarrows]. Kyiv: Naukova Dumka [in Russian].

Chernogorod, L. B., & Vinogradov, B. A. (2006). E`firnye masla vidov roda Achillea (Asteraceae), soderzhashhie fragranol [Essential oils of genus Achillea (Asteraceae) species containing fragranol]. Rastitelnye resursy, 2(42), 61–68 [in Russian].

Todorova, M., Trendafilova, A., Mikhova, B., Vitkova, A., & Duddeck, H. (2007). Chemotypes in Achillea collina based on sesquiterpene lactone profile. Phytochemistry, 68(13), 1722–1730.

Ehrendorfer, F., & Guo, Y. (2006). Multidisciplinary studies on Achillea sensu lato (Compositae-Anthemideae): new data on systematics and phylogeography. Willdenowia, 36(1), 69.

Glasla, S., Mucaji, P., Werner, I., Presser, A., & Jurenitsch, J. (2002). Sesquiterpenes and Flavonoid Aglycones from a Hungarian Taxon of the Achillea millefolium Group. Z. Naturforsch, 11–12(57), 976–982.

How to Cite

1.
Smoilovskaya GP, Mazulin AV, Svetashov OM. The bacteriostatic activity of essential oils for some specimen Millefolium Koch. genus Achillea L. Current issues in pharmacy and medicine: science and practice [Internet]. 2014Nov.12 [cited 2024Dec.23];(3). Available from: http://pharmed.zsmu.edu.ua/article/view/32852

Issue

Section

Pharmacognosy and chemistry of natural compounds