Chromatography-mass spectrometric study of Arceuthobium oxicedri raw material

Authors

DOI:

https://doi.org/10.14739/2409-2932.2025.1.321193

Keywords:

juniper dwarf mistletoe, liquid chromatography-mass spectrometry, plant extract, qualitative composition, quantitative composition

Abstract

Arceuthobium oxycedri, M. Bieb., commonly known as dwarf mistletoe, is widespread in the Mediterranean region, parasitizing the branches of Juniperus oxycedrus as a host plant. Compared to white mistletoe, it is more aggressive. It exhibits antibacterial, antifungal, phytotoxic, cytotoxic, and insecticidal activities.

Aim. The study aimed to investigate the qualitative and quantitative composition of biologically active substances and the biological activity of the methanol extract of juniper dwarf mistletoe (Arceuthobium oxicedri, M. Bieb.) as a potential source of medicinal substances.

Materials and methods. The object of the study was the shoots and branches of juniper dwarf mistletoe collected during the fruiting phase. The qualitative and quantitative determination of components was carried out at the Department of Toxicological and Inorganic Chemistry, Zaporizhzhia State Medical and Pharmaceutical University.

Results. Chromatography-mass spectrometric analysis of juniper dwarf mistletoe identified 34 components, the main ones being γ-curcumin (20.405 %), cedrol (17.619 %), epimanoyl oxide (5.142 %), and humulene (3.893 %).

Conclusions. The data obtained indicate the significant value of juniper dwarf mistletoe as a source of biologically active compounds, providing a basis for further study to develop promising medicinal substances.

Author Biographies

O. I. Panasenko, Zaporizhzhia State Medical and Pharmaceutical University

PhD, DSc, Professor, Head of the Department of Toxicological and Inorganic Chemistry

V. M. Odyntsova, Zaporizhzhia State Medical and Pharmaceutical University

PhD, DSc, Professor of the Department of Pharmacognosy, Pharmacology and Botany

O. M. Denysenko, Zaporizhzhia State Medical and Pharmaceutical University

PhD, Associate Professor of the Department of Pharmacognosy, Pharmacology, and Botany

V. I. Mozul, Zaporizhzhia State Medical and Pharmaceutical University

PhD, Associate Professor of the Department of Pharmacognosy, Pharmacology, and Botany

V. V. Holovkin, Zaporizhzhia State Medical and Pharmaceutical University

PhD, Associate Professor of the Department of Pharmacognosy, Pharmacology, and Botany

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Published

2025-03-10

How to Cite

1.
Panasenko OI, Odyntsova VM, Denysenko OM, Mozul VI, Holovkin VV. Chromatography-mass spectrometric study of Arceuthobium oxicedri raw material. Current issues in pharmacy and medicine: science and practice [Internet]. 2025Mar.10 [cited 2025Apr.17];18(1):12-6. Available from: http://pharmed.zsmu.edu.ua/article/view/321193