Clinical and marketing analysis of consumer behavior in the market of topical antifungal agents for the treatment of vulvovaginal candidiasis in Ukraine

Authors

DOI:

https://doi.org/10.14739/2409-2932.2026.1.349541

Keywords:

medicinal products, antifungal drugs, vaginal infections, marketing research, clinical marketing analysis, survey, consumer demand, vaginal candidiasis, pharmaceutical market

Abstract

The high prevalence of vaginal candidiasis among women of reproductive age (75–90 %), the tendency to self-medication and the active use of over-the-counter antimycotic drugs lead to an increase in the medical, social and pharmaceutical significance of this problem. In the context of the transformation of the pharmaceutical market, changes in consumer behavior and the development of online sales channels, a comprehensive analysis of the topical antimicotic drugs market is becoming especially relevant. This study is aimed at substantiating current trends, selection factors and prospects for the development of the range, considering the needs of different groups of consumers.

The aim of the study is to conduct a clinical marketing analysis and investigate consumer segmentation of the topical antifungal drug market for the treatment of vaginal infections, with a focus on behavioral patterns, factors influencing the choice of dosage forms, and self-medication practices among women of reproductive age.

Materials and methods. The materials of the study were open sources of information on the market of topical antimycotic drugs for the treatment of vaginal infections, in particular, state registers of medicines of Ukraine, analytical reports of pharmaceutical companies, scientific publications and data on consumer preferences obtained based on questionnaires of respondents.

Results. The work carried out a marketing and segmentation analysis of the pharmaceutical market of topical antimycotic drugs intended for the therapy of vaginal infections. The modern structure of the market was studied, the main manufacturers were identified, the share of domestic and foreign drugs was estimated, and key trends in the development of the segment were identified. Particular attention is paid to the analysis of consumer demand, which allows us to outline the prospects for expanding the range, increasing the competitiveness and effectiveness of marketing strategies.

Conclusions. The market for topical antimicotic drugs is characterized by stable demand due to the high prevalence of vaginal candidiasis and the predominance of self-treatment with OTC (over-the-counter) drugs, which actualizes the expansion of the range of dosage forms. Consumer behavior depends on socio-demographic factors: young women are more likely to choose combination drugs, while lower-income consumers focus on availability and price, which creates opportunities for differentiated strategies. The growth of online distribution along with the dominance of traditional pharmacies and a significant share of relapses determines the need for educational programs, innovative combined tools and adaptation of logistics and regulatory approaches.

Author Biographies

T. V. Mielnyk, Zaporizhzhia State Medical and Pharmaceutical University

Postgraduate Student of the Department of Medicinal Preparations Technology

V. V. Gladyshev, Zaporizhzhia State Medical and Pharmaceutical University

PhD, DSc, Professor, Head of the Department of Medicinal Preparations Technology

References

Rosati D, Bruno M, Jaeger M, Ten Oever J, Netea MG. Recurrent Vulvovaginal Candidiasis: An Immunological Perspective. Microorganisms. 2020;8(2):144. doi: https://doi.org/10.3390/microorganisms8020144

Denning DW, Kneale M, Sobel JD, Rautemaa-Richardson R. Global burden of recurrent vulvovaginal candidiasis: a systematic review. Lancet Infect Dis. 2018;18(11):e339-e347. doi: https://doi.org/10.1016/S1473-3099(18)30103-8

Schaller M, Schackert C, Korting HC, Januschke E, Hube B. Invasion of Candida albicans correlates with expression of secreted aspartic proteinases during experimental infection of human epidermis. J Invest Dermatol. 2000;114(4):712-7. doi: https://doi.org/10.1046/j.1523-1747.2000.00935.x

Willems HM, Ahmed SS, Liu J, Xu Z, Peters BM. Vulvovaginal Candidiasis: A Current Understanding and Burning Questions. J Fungi (Basel). 2020;6(1):27. doi: https://doi.org/10.3390/jof6010027

Valentine M, Wilson D, Gresnigt MS, Hube B. Vaginal Candida albicans infections: host-pathogen-microbiome interactions. FEMS Microbiol Rev. 2025;49:fuaf013. doi: https://doi.org/10.1093/femsre/fuaf013

Akinosoglou K, Livieratos A, Asimos K, Donders F, Donders G. Fluconazole-Resistant Vulvovaginal Candidosis: An Update on Current Management. Pharmaceutics. 2024;16(12):1555. doi: https://doi.org/10.3390/pharmaceutics16121555

Anh DN, Hung DN, Tien TV, Dinh VN, Son VT, Luong NV, et al. Prevalence, species distribution and antifungal susceptibility of Candida albicans causing vaginal discharge among symptomatic non-pregnant women of reproductive age at a tertiary care hospital, Vietnam. BMC Infect Dis. 2021;21(1):523. doi: https://doi.org/10.1186/s12879-021-06192-7

Ratner JC, Wilson J, Roberts K, Armitage C, Barton RC. Increasing rate of non-Candida albicans yeasts and fluconazole resistance in yeast isolates from women with recurrent vulvovaginal candidiasis in Leeds, United Kingdom. Sex Transm Infect. 2025;101(1):21-6. doi: https://doi.org/10.1136/sextrans-2024-056186

Nyirjesy P, Schwebke JR, Angulo DA, Harriott IA, Azie NE, Sobel JD. Phase 2 Randomized Study of Oral Ibrexafungerp Versus Fluconazole in Vulvovaginal Candidiasis. Clin Infect Dis. 2022;74(12):2129-35. doi: https://doi.org/10.1093/cid/ciab841

Workowski KA, Bachmann LH, Chan PA, Johnston CM, Muzny CA, Park I, et al. Sexually Transmitted Infections Treatment Guidelines, 2021. MMWR Recomm Rep. 2021;70(4):1-187. doi: https://doi.org/10.15585/mmwr.rr7004a1

Recommendations for the treatment of Trichomonas vaginalis, Mycoplasma genitalium, Candida albicans, bacterial vaginosis and human papillomavirus (‎anogenital warts)‎ [Internet]. Who.int. World Health Organization; 2024 [cited 2025 Dec 10]. Available from: https://www.who.int/publications/i/item/9789240096370

Centers for Disease Control and Prevention. Bacterial vaginosis [Internet]. Cdc.gov. 2022 [cited 2025 Dec 10]. Available from: https://www.cdc.gov/std/treatment-guidelines/bv.htm

Centers for Disease Control and Prevention. Vulvovaginal candidiasis - STI Treatment Guidelines [Internet]. Cdc.gov. 2021 [cited 2025 Dec 10]. Available from: https://www.cdc.gov/std/treatment-guidelines/candidiasis.htm

Davydova IV, Limanskaya AY, Kravets OM, Tarnavska AA. [Role of dual therapy on the repeated episode of vulvovaginal candidiasis]. Ukrainian Journal of Perinatology and Pediatrics. 2020;(1):27-33. Ukrainian. doi: https://doi.org/10.15574/PP.2020.81.27

Kalugina L, Tatarchuk T, Shmulian I. [Bacterial vaginosis: modern view of the problem and its status in Ukraine]. Reproductive Endocrinology. 2021;(3):72-7. Ukrainian. doi: https://doi.org/10.18370/2309-4117.2021.59.72-77

Bushuieva IV, Prytula RL, Shmatenko OP, Parchenko VV. [The application of the concept of trust marketing in the study of price sensitivity to study the consumer value of topical antifungal agents in the dosage form "gel"]. Current issues in pharmacy and medicine: science and practice. 2025;18(1):69-74. Ukrainian. doi: https://doi.org/10.14739/2409-2932.2025.1.307838

Okseniuk OY, Gudzenko OP, Shpychak OS. The analysis of the pharmaceutical market of antifungal drugs in Ukraine. Social marketing and pharmacoeconomic research. 2020;6(1):69-80. Ukrainian. doi: https://doi.org/10.24959/sphhcj.20.169

Additional Files

Published

2026-03-16

How to Cite

1.
Mielnyk TV, Gladyshev VV. Clinical and marketing analysis of consumer behavior in the market of topical antifungal agents for the treatment of vulvovaginal candidiasis in Ukraine. Current issues in pharmacy and medicine: science and practice [Internet]. 2026Mar.16 [cited 2026Mar.17];19(1):60-8. Available from: https://pharmed.zsmu.edu.ua/article/view/349541