Mineral density of the radius and tibia in children depending on age, sex, and susceptibility to fractures according to ultrasound densitometry data

Authors

DOI:

https://doi.org/10.14739/2409-2932.2026.1.345055

Keywords:

children, bones, ultrasound densitometry, osteopenia, fractures

Abstract

The aim of the work is to study the speed of ultrasound propagation in bones to determine the state of osteopenia and osteoporosis in children taking into account age, gender, physical development, and susceptibility to traumatic fractures.

Materials and methods. A total of 142 children aged 1 to 17 years were studied, of which 61 were girls and 81 were boys. Positive answers to questions about unbalanced nutrition, refusal to take vitamin D and repeated traumatic, primarily so-called low-energy fractures in the past were the basis for conducting ultrasound densitometry of bone density in children. To measure the speed of ultrasound waves in the tissues of the radius and tibia, the Mini-Omni device made in Israel was used.

Results. The average ultrasound propagation velocity in the radius and tibia in children depended on age, sex, and body mass index. The Z-scores, which took these relationships into account, were below the reference values (Z-score <-1.0) in almost all age categories except for adolescent girls aged 13–17 years. Boys and young men with Z-scores below -1.0 had twice the frequency of recurrent low-energy bone fractures in the past, compared with other children.

Conclusions. The method of measuring the speed of propagation of ultrasound in the form of the Z-score indicator is a convenient, fast and safe method of screening the state of bone mineral density in children and allows to detect osteopenia of varying degrees in 66.2 % of randomly examined children. In boys and young men aged 8–17 years, a Z-score below -1.0 doubles the risk of low-energy fracture.

Author Biographies

O. H. Ivanko, Zaporizhzhia State Medical and Pharmaceutical University

DSc, MD, Professor, The Head of the Department of Propaedeutic of Children Diseases

V. A. Deineha, Zaporizhzhia State Medical and Pharmaceutical University

Assistant of the Department of Propaedeutics of Children Diseases

M. V. Patsera, Zaporizhzhia State Medical and Pharmaceutical University

MD, Associate Professor of the Department of Propaedeutics of Children Diseases

O. V. Solianyk, Zaporizhzhia State Medical and Pharmaceutical University

MD, Assistant of the Department of Propaedeutics of Children Diseases

V. Ya. Pidkova, Zaporizhzhia State Medical and Pharmaceutical University

MD, Associate Professor of the Department of Propaedeutics of Children Diseases

References

Antypkin YH, Volosovets OP, Maidannyk VH, Berezenko VS, Moiseienko RO, Vyhovska OV, et al. [Status of child population health - the future of the country (part 1)]. Child`s health. 2018;13(1):1-11. Ukrainian. doi: https://doi.org/10.22141/2224-0551.13.1.2018.127059

Osman NS. [Optimization of diagnosis and forecasting of structural and functional disorders of bone tissue in children during period of growth spurt] [dissertation on the Internet]. Kharkiv: Kharkiv National Medical University; 2022 [cited 2025 Dec 14]. Ukrainian. Available from: https://knmu.edu.ua/wp-content/uploads/2022/12/osman_dys.pdf

Marushko YV, Volokha TI, Asonov AA. [Ultrasound densitometry (axial dimension) in the diagnosis of osteopenia syndrome in children with various somatic pathology]. Sovremennaya pediatriya. 2016;(1):54-8. Ukrainian. Available from: https://med-expert.com.ua/journals/wp-content/uploads/2017/06/12-8.pdf

Plaksa V. [Modern markers of osteodysmetabolic syndrome]. Actual Problems of the Modern Medicine. 2023;23(2.1):67-3. Ukrainian. doi: https://doi.org/10.31718/2077-1096.23.2.1.67

MiniOmni™ Bone Densitometer. MedMax.com.ua. [cited 2025 Dec 14]. Available from: https://medmax.com.ua/equipment/densitometer/miniomni.html

Osteoporosis Management HEDIS OMW. BeamMed Ltd.; 2019. Available from: https://www.beammed.com/wp-content/uploads/2021/12/HEDIS-brochure.pdf

Koski A-M. [Guideline 00419. Osteoporosis]. Duodecim Medical Publications, Ltd. Ukrainian. Available from: https://guidelines.moz.gov.ua/documents/3278

Ferjani HL, Cherif I, Nessib DB, Kaffel D, Maatallah K, Hamdi W. Pediatric and adult osteoporosis: a contrasting mirror. Ann Pediatr Endocrinol Metab. 2024;29(1):12-8. doi: https://doi.org/10.6065/apem.2346114.057

Tsymbal A, Kotlova J. [Condition of bone mineral density in newborns and their mothers of different age groups]. Neonatology, surgery and perinatal medicine. 2021;11(2):17-20. Ukrainian. doi: https://doi.org/10.24061/2413-4260.XI.2.40.2021.3

Grischenko OV, Jarkikh AV, Amro IG, Kirilyuk AD, Avramenko NV, Malishev VE. [Diagnosis of osteopenia syndrome in pregnancy and parturition]. Reproductive Health of Woman. 2007;(5):90-4. Ukrainian.

Povoroznyuk VV, Musiyenko AS, Dzerovich NI. [Mineral density and quality of bone tissue, 10-year risk of osteoporotic fractures among ukrainian men of various ages]. Pain, joints, spine. 2013;(3):52-5. Ukrainian. doi: https://doi.org/10.22141/2224-1507.3.11.2013.82345

Additional Files

Published

2026-03-16

How to Cite

1.
Ivanko OH, Deineha VA, Patsera MV, Solianyk OV, Pidkova VY. Mineral density of the radius and tibia in children depending on age, sex, and susceptibility to fractures according to ultrasound densitometry data. Current issues in pharmacy and medicine: science and practice [Internet]. 2026Mar.16 [cited 2026Mar.17];19(1):54-9. Available from: https://pharmed.zsmu.edu.ua/article/view/345055