Assessment of the availability of topical antibacterial drugs used in dermatology
DOI:
https://doi.org/10.14739/2409-2932.2026.1.341749Keywords:
pyoderma, dermatology, medicines, market research, pharmaceutical marketAbstract
Skin diseases caused by the functioning of pathogenic and saprophytic bacteria are characterized by nosological diversity. One of the most common pathologies in this group, which dermatologists encounter almost daily and in all age groups, is pustular skin diseases or pyoderma. Expanding the arsenal of pharmacotherapeutic agents that provide effective etiotropic treatment of superficial forms of pyoderma while preventing their further dissemination is one of the pressing issues of modern dermatology. Given the difficult circumstances that arose in connection with military operations and which directly affect the quality of pharmaceutical provision of medicines to the population of cities and villages, the analysis of accessibility (physical and economic) for Ukrainian patients remains relevant.
The aim of the work is to assess the availability of local antibacterial drugs used in dermatology.
Materials and methods. The information base of the study was the National List of Essential Medicines; open statistical resources of the Ministry of Health of Ukraine; tabletki.ua and online data of pharmacy chains; instructions for medical use of drugs. The study used methods such as information search, analysis, generalization, and marketing research.
Results. From the list of local antibacterial drugs, 35 trade names of the most in-demand medicines were identified for further analysis. No significant differences in physical availability were found between frontline, central, and western regions. This indicates the restoration of pharmaceutical logistics processes compared to the beginning of 2022, despite the protracted nature of the military conflict. Based on the conducted research, several structured measures are proposed to improve the management of the range of medicines and improve pharmaceutical care.
Conclusions. It was found that the physical availability of local antibacterial drugs is 82 %, with minor regional differences between frontline, central and western cities of Ukraine, which indicates the restoration of logistical processes and pharmaceutical supply of the retail segment of the Ukrainian pharmaceutical market. It was found that the economic accessibility of local antibacterial drugs is high (all drugs are classified as highly accessible, the solvency adequacy ratio is less than 5 %), but the calculations are based on the average salary, which does not consider regional disparities, which may overestimate real accessibility.
References
Reese AM, Haag CK, Jung E, Nauta AC, Swerlick RA, Ortega-Loayza AG. Pyoderma gangrenosum underrepresentation in non-dermatological literature. Diagnosis (Berl). 2020;8(1):85-90. doi: https://doi.org/10.1515/dx-2019-0079
Hou YL, Lee CH. Pyoderma Gangrenosum. JAMA Dermatol. 2022;158(2):202. doi: https://doi.org/10.1001/jamadermatol.2021.5001
Wang H, Bai Z, Shen C, Kou J, Zhu Y, Xie H, et al. The global, regional, and national patterns of change in the burden of bacterial pyoderma from 1990 to 2019 and the forecast for the next decade. Sci Rep. 2025;15(1):1810. doi: https://doi.org/10.1038/s41598-025-85995-z
Narla S, Silverberg JI. The inpatient burden and comorbidities of pyoderma gangrenosum in adults in the United States. Arch Dermatol Res. 2021;313(4):245-53. doi: https://doi.org/10.1007/s00403-020-02098-7
Leal JM, de Souza GH, Marsillac PF, Gripp AC. Skin manifestations associated with systemic diseases - Part II. An Bras Dermatol. 2021;96(6):672-87. doi: https://doi.org/10.1016/j.abd.2021.06.003
Diaconescu S, Strat S, Balan GG, Anton C, Stefanescu G, Ioniuc I, et al. Dermatological Manifestations in Pediatric Inflammatory Bowel Disease. Medicina (Kaunas). 2020;56(9):425. doi: https://doi.org/10.3390/medicina56090425
Mate Y, Sarkar PK, Lodh C, Isore DP, Biswas U, Sarkar S. Point prevalence of canine pyoderma of Staphylococcus aureus origin and its management by antibiotics and Gandhaka Druti. J Drug Res Ayurvedic Sci. 2022;7(3):168-74. doi: https://doi.org/10.4103/jdras.jdras_63_22
Caldarola G, Traini DO, Falco GM, Chiricozzi A, De Luca E, Mannino M, et al. Clinical, epidemiological, and therapeutic hallmarks of pyoderma gangrenosum: a case series of 35 patients. Int J Dermatol. 2024;63(9):1185-92. doi: https://doi.org/10.1111/ijd.17093
Demchenko VO, Tkachenko NO, Demchenko VO. [Research of the current state of the market of vitamin and mineral complexes for pregnant women and information support for women during pregnancy]. Current issues in pharmacy and medicine: science and practice 2022;15(3):330-6. Ukrainian. doi: https://doi.org/10.14739/2409-2932.2022.3.259188
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