The organs of male reproductive system and correction of disorders in a large industrial city (Zaporozhye and Zaporozhye region)
DOI:
https://doi.org/10.14739/2409-2932.2015.3.52654Keywords:
Male Infertility, Spermatogenesis, Environmental Pollution, SemenAbstract
The study of male reproductive health is relevant, because it is one of the leading causes of the demographic crisis and depopulation of the Ukrainian nation. The article highlights the problems of male infertility, in particular, the question regarding the reasons of the decline in men reproductive potential under the influence of adverse conditions of the industrial city.
Aim. The purpose is to study the factors of male infertility in Zaporozhye and Zaporozhye region, the relationship between the area of residence and occupational status.
Methods and results. The analysis of ejaculate indicators in men, living in ecologically unfavorable areas and regularities that reflect the pathogenetic mechanisms of occurrence and development of violations of gametogenesis and the functional inferiority of the sex cells have been studied.
Conclusion. This shows the increasing trend of male factor infertility, which is from 40% to 60%, and the demographic losses in Ukraine.
References
Bazalytska, S. V., & Nikitin, O. D. (2012) Imunohistokhimichne vyznachennia porushen spermatohenezu u cholovikiv iz zabrudnenykh radionuklidamy rehioniv [Managesthe viznachennya poruseni spermatogenesis in cholov zabrudnennya radonuclides with governments of regions]. Zdorov'e muzhchiny, 1, 95–99. [in Ukrainian].
Arav, V. I., Slesareva, E. V., Slesarev, S. M., & Sych, V. F. (2011) Bioaktivnye veschestva e′pifiza v regulyacii spermatogeneza [Pineal Gland and the Regulation of Spermatogenesis]. Vestnik novykh medicinskikh tekhnologij, 13(1), 112–114. [in Russian].
Bugaeva, L. I., Spasov, A. A., & Kuzubova, E. A. (2012). Vliyanie bemitila na polovoe povedenie i spermatogenez krys [The Influence of Bemithyl on the Sexual Behavior and Spermatogenesis in Rats]. E′ksperimental'naya i klinicheskaya farmakologiya, 69(1), 38–41. [in Russian].
Bykov, V. L. (2010) Spermatogenez u muzhchin v konce XX veka (obzor literatury) [Spermatogenesis in men in the late twentieth century (literature review)]. Problemy reprodukcii, 1, 6–13. [in Russian].
Galimov, Sh. N., Amirova, Z. K., & Galimova, E′. F. (2011) «Krizis spermatozoida» i tekhnogennoe zagryaznenie okruzhayuschej sredy: fakty i gipotezy [«Sperm crisis» and technogenic environmental pollution: facts and hypotheses]. Problemy reprodukcii, 2, 19–22. [in Russian].
Sakalo, A. V., Bazalickaja, S. V., Sakalo, V. S., Grigorenko, V. N., Bondarenko, Yu. N., & Nedel'chev, V. S. (2011) Gormonal'naya i spermatogennaya funkciya u bol'nykh s neseminomnymi opukholyami yaichka v stadii 1-2A posle odnostoronnej orhie′ktomii i khimioterapii [Hormonal and spermatogenic function in patients with testicular seminoma stage in 1-2A after unilateral orchiectomy and chemotherapy]. Zdorov'e muzhiny, 4, 160–162. [in Ukrainian].
Zolotukhyn, V. N. (2013) Oksydatyvnyi stres yak faktor porushennia spermatohenezu [Oxidative stress as a factor in the impairment of spermatogenesis] Problemy endokrynnoi patolohii, 1, 13–17. [in Ukrainian].
Bondarenko, V. A., Minukhin, A. S., Kozhemyaka, V. A., & Skornyakov, E. I. (2010) Izuchenie rezervnoj funkcii semennikov u muzhin s gipoandrogennym statusom [The study of backup functions of the testes in men with hypoandrogenism status]. Zdorov'e muzhiny, 3, 90–92. [in Ukrainian].
Korenieva, Ye. M., Karpenko, N. O., Yaremenko, F. H., Kustova, S. P., & Seliukova, N. Yu. (2011) Kadmii: problemy cholovichoho zdorovia ta zasoby yoho korektsii [Cadmium: problems of male health and means of its correction] Zdorov'e muzhiny, 1, 87–90. [in Ukrainian].
Kurilo, L. F., Evdokimov, V. V., Erasova, V. S. (2000) Vliyanie oblucheniya na sostoyanie spermatogeneza roditelej i potomstva [Effect of irradiation on the spermatogenesis status of parents and offspring]. Problemy reprodukcii, 1, 35–38. [in Russian].
Lesovoj, V. N., Knigavko, V. A., & Arkatov, A. V. (2012) Znachenie antispermal'nykh antitel v formirovanii muzhskogo besplodiya [The significance of antisperm antibody formation in male infertility]. Vrachebnaya praktika, 6, 45–47. [in Ukrainian].
Liulko, O. V., Prokhorenko, O. V., & Kozlovskyi, I. V. (2012) Aminokyslotnyi spektr spermalnoi plazmy i znachennia yoho u bezplidnomu shliubi [Amino acid spectrum in plasma and the value of it in a fruitless marriage]. Urolohiia, 1, 63–75. [in Ukrainian].
Vasil'ev, V. S., et al. (2011) Morfometricheskie i kineticheskie pokazateli spermy cheloveka do i posle vozdejstviya nizkikh temperatur pri razlichnykh sostoyaniyakh spermatogeneza [Morphometric and kinetic characteristics of sperm of the person before and after exposure to low temperatures at various States of spermatogenesis]. Zdorov'e muzhiny, 2, 184–186. [in Ukrainian].
Bocharova, E. N. Shilejko, L.V., Bragina, E. E. (2010) Narushenie spermatogeneza cheloveka: kolichestvennoe issledovanie sostava nezrelykh polovykh kletok pri inficirovanii spermatozoidov virusom prostogo gerpesa [Violation of human spermatogenesis: a quantitative study of the immature germ cells during infection of sperm cells by the herpes simplex virus]. Problemy reprodukcii, 12(6), 75–80. [in Russian].
Nejmark, A. I., Aliev, R. T., Nozdrachev, N. A., Krainichenko, S. V., Elchaninova, S. A., Zolovkina, A. G., et al. (2008) Narusheniya spermatogeneza i ikh korrekciya u bol'nykh khronicheskim abakterial'nym prostatitom [Defects in spermatogenesis and their correction in patients with chronic abacterial prostatitis]. Urologiya, 1, 40–45. [in Russian].
Naumenko, V. A., Tyulenev, Yu. A., Pushkar, D. Yu., Segal, A. S., Kovalev, V. A., Kurilo, L. F., et al. (2011) Vliyanie virusa prostogo gerpesa na spermatogenez [Effect of Herpes Simplex virus on spermatogenesis]. Urologiya, 6, 32–36. [in Russian].
Nikitin, O. D., & Bazalickaya, S. V. (2011) Anomalii polovykh khromosom pri muzhskoj infertil'nosti [Anomalies of sex chromosomes in male infertility]. Zdorov'e muzhiny, 4, 151–155. [in Ukrainian].
Bozhedomov, V. A., Gromenko, D. S., Ushakova, I. V., Toroptseva, M. V., Galimov, Sh. N., Alexandrova, L. A., et al. (2009) Oksidativnyj stress spermatozoidov v patogeneze muzhskogo besplodiya [Oxidative stress of spermatozoa in pathogenesis of male infertility]. Urologiya, 2, 51–56. [in Russian].
Gorpinchenko, I. I., Bazalickayja, O. D., Nikitin, S. V., Gontar', Yu. V., Il'in, I. E. (2012) Ocenka kachestvennykh pokazatelej e′jakulyata u pacientov s besplodiem [Evaluation of quality indicators of the ejaculate from patients with infertility] Zdorov'e muzhiny, 3, 112–115. [in Ukrainian].
Pastukhova, V. A. (2008) Kharakterystyka strukturnykh zmin v yaiechku pry khronichnii hipertermii [Characterization of structural changes in the testis during chronic hyperthermia]. Tavricheskij mediko-biologicheskij vestnik, 12(1)(45), 141–143. [in Ukrainian].
Potemina, T. E., & Tukmakova, T. S. (2011) Vliyanie teplovogo vozdejstviya na spermatogenez v e′ksperimente [The Influence of thermal effects on spermatogenesis in xperimenta]. Sovremennye tekhnologii v medicine, 4, 99–101. [in Russian].
Velychko, N. F., et al. (2012) Rozvytok oksydatyvnoho stresu ta porushennia spermatohenezu v doroslykh samtsiv shchuriv, shcho zaznaly dii m’iakoho emotsiinoho stresu v period molochnoho vyhodovuvannia [The development of oxidative stress and impairment of spermatogenesis in adult male rats subjected to the action of mild emotional stress in the period of milk feeding]. Problemy endokrynnoi patolohii, 4, 91–95. [in Ukrainian].
Glybochko, P., Alyaev, Yu., Chalyi, M., Grigoryan, V., Barashkov, G., & Usacheva, O. (2013) Rol' narusheniya metalloligandnogo gomeostaza v razvitii patozoospermii posle operativnogo lecheniya varikocele [Role of impaired Metal ligand homeostasis in the development of abnormal zoospermia after surgical treatment for varicocele]. Vrach, 1, 33–35. [in Russian].
Alzlkovlch, B. I., Alzlkovlch, I. V., Verba, O. Yu., & Kozlov, V. A. (2008) Rol' citokinov v regulyacii spermatogeneza: sovremennyj vzglyad na problemu [Cytokine role in spermatogenesis: modern opinion on prob1em]. Immunologiya, 29(3), 191–192. [in Russian].
Ryzhakov, I. D. (2013) Muzhskoe besplodie: real'nost' i perspektivy: Aktovaya rech' [Male infertility: reality and prospects: commencement speech]. N. Novgorod: NGMA. [in Russian].
Evdokimov, V. V., Kharlamova, L. A., Aĭbiatov, D. T., Turovetskiĭ, V. B., & Erokhin, A. S. (2012) Sopostavlenie metodov i uslovij dlya kachestvennoj ocenki spermatozoidov cheloveka [The comparison of two methods for detection of human spermatozoa with damaged membrane]. Problemy reprodukcii, 3, 68–71. [in Russian].
Arav, V. I., Denisova, O. F., Zheleznyak, E. V., & Slesarev, S. M. (2013) Sutochnaya periodichnost' spermatogennogo cikla [Daily periodicity of the spermatogenic cycle]. Vestnik novykh medicinskikh tekhnologij, 3, 11–12. [in Russian].
Slonimskij, B. Yu., Kovalev, V. A., Komov, R. V., & Vinokurov, V. V. (2012) Fertil'nost' u muzhchin: diagnostika i lechenie pri metabolicheskom sindrome [Fertility in men: diagnosis and treatment in metabolic syndrome]. Lechaschij vrach, 5, 65–67. [in Russian].
Cvetkova, P., Babyuk, I., Ivanova, S., & Ilieva, I. (2012) Citogeneticheskoe issledovanie e′yakulyata pri muzhskom besplodii [Cytogenetic study of ejaculate in male infertility]. Zdorov'e muzhiny, 3, 116–117. [in Ukrainian].
Kohn, F. M., & Haidl, G. (2011) Andrological diagnostics. Urology, 46(11), 1557–1572.
Matzuk, M. M., & Lamb, D. J. (2013) The biology of infertility: research advances and clinical challenges. Nat. Med., 14(11), 1197–1213.
Teppa-Garran, A. D., & Palacios-Torres, A. (2013) Current evaluation of male infertility. Invest. Clin., 45(4), 355–370.
De Martino, M. U., Pastore, R., Caprio, M., Frajese, G., & Fabbri, A. (2003) Dinaming testing in the evaluation of male gonadol function. J. Endocrinol. Invest., 26(7), 107–113.
Nieschlag, E., Simoni, M., Gromoll, J., & Weinbauer GF. (1999) Role of FSH in the regulation of spermatogenesis: clinical aspect. Clin. Endocrinol., 51, 139–146. doi: 10.1046/j.1365-2265.1999.00846.x.
Sigman, M. (2008) How involved should the urologist be in the evolution and management of male infertility. J. Urol., 180(5), 1888–1889.
Simoni, M., Tüttelmann, F., Michel, C., Böckenfeld, Y., Nieschlag, E., & Gromoll, J. (2008) Polymorphisms of the luteinizing hormone/chorionic gonadotropic receptor gene: association with maldescended testes and male infertility. Pharmacogenet. Genomics, 18(3), 193–200. doi: 10.1097/FPC.0b013e3282f4e98c.
Wang, C., Mc Donald, E., Leung, A., Superlano, E., Berman, N., Hull, L., & Swerdloff, R. S. (1997) Effect of increased scrotal temperature on sperm production in normal man. Fertil. Steril, 68(24), 334–339. doi:10.1016/S0015-0282(97)81525-7.
Delaware, E. M., Felius, B., Delemarre-van de Waal, H. A. (2008) Inducing puberty. Eur. J. Endocrinol, 159(1), S9–S15. doi: 10.1530/EJE-08-0314.
Downloads
How to Cite
Issue
Section
License
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access)
