Cardiorenal syndrome in patients with chronic heart failure
DOI:
https://doi.org/10.14739/2409-2932.2015.2.45201Keywords:
Cardiorenal Syndrome, Heart Failure, Coronary Heart Disease, HypertensionAbstract
Aim. The relevance of the chosen research direction is stipulated by increasing prevalence of chronic cardiovascular disease and states associated with it.
Methods and results. In order to evaluate the filtration function of the kidneys in patients with CHF there were examined 40 male patients with a verified disorder of left ventricular systolic function, occurred at a background of coronary heart disease and hypertension and 30 healthy individuals of the same age with determination of glomerular filtration rate (GFR) by endogenous creatinine clearance. It is shown that in patients with impaired left ventricular systolic function in the background of coronary heart disease and hypertension the chronic kidney disease is manifested. The concentration of creatinine in patients ranged reference values 85,2 ±0,4 mmol / l, and the glomerular filtration rate is closely correlated (r=0,60) with the degree of violation of left ventricular systolic function.
Conclusion. This indicates the formation of cardiorenal syndrome encumbrance and mutual pathologies of the cardiovascular system and chronic kidney disease.
References
Chung ES, Meyer TE. Cardiorenal syndrome: misgivings about treatment options, clarity on prognosis. J Card Fail. 2015 Feb;21(2):116-8
De Vecchis R, Baldi C. Cardiorenal syndrome type 2: from diagnosis to optimal management. Ther Clin Risk Manag. 2014 Nov 12;10:949-61
Demesova E, Goncalvesova E, Slezak P, Pontuch P. Functional and circulatoryrenal changes in advanced heart failure. Bratisl Lek Listy. 2015;116(2):83-7
Iacoviello M, Leone M, Antoncecchi V, Ciccone MM. Evaluation of chronic kidneydisease in chronic heart failure: From biomarkers to arterial renal resistances. World J Clin Cases. 2015 Jan 16;3(1):10-9
Onuigbo MA. RAAS inhibition and cardiorenal syndrome. Curr Hypertens Rev.2014;10(2):107-11.
Pollock E, Nowak A. The cardiorenal problem. Swiss Med Wkly. 2014 Dec4;144:w14051
Tsuruya K, Eriguchi M. Cardiorenal syndrome in chronic kidney disease. CurrOpin Nephrol Hypertens. 2015 Mar;24(2):154-62
Gori M, Senni M, Gupta DK, Charytan DM, Kraigher-Krainer E, Pieske B, ClaggettB, Shah AM, Santos AB, Zile MR, Voors AA, McMurray JJ, Packer M, Bransford T,Lefkowitz M, Solomon SD; PARAMOUNT Investigators. Association between renalfunction and cardiovascular structure and function in heart failure withpreserved ejection fraction. Eur Heart J. 2014 Dec 21;35(48):3442-51
KamyshnikovVSGuide toClinical and biochemicalresearch andlaboratory diagnosis. Moscow,2009.MEDpress-Inform. 889p.
STATISTICA 10.0 Retrieved from:http://www.statsoft.com
Downloads
How to Cite
Issue
Section
License
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access)