Clinical features of coronary heart disease in postmenopausal women, depending on the degree of bone mineral density loss

Authors

  • N. S. Mykhailovskaya
  • I. O. Shevchenko
  • O. V. Nikituk

DOI:

https://doi.org/10.14739/2409-2932.2015.2.45106

Keywords:

Coronary Artery Disease, Postmenopausal Period, Osteoporosis, Osteopenia, Bone Mineral Density, Correlation Of Data

Abstract

Coronary artery disease (CAD) is one of the most urgent problems of the modern cardiology.

Aim. In order to explore the clinical features of the coronary artery disease, depending on the degree of bone mineral density loss the study included 43 women in postmenopausal period.

Methods and results. Group 1 - 10 patients with coronary artery disease concomitant with osteopenia, 2 group- 12 CAD patients with osteoporosis; Group 3 (comparisons) - 21 CAD patients with normal BMD. With the help of ultrasound densitometry, echocardioscopy, Seattle Angina Questionnaire we investigated the BMD state, structural and functional state of the heart, life quality of the patients. It has been found that the coronary artery disease concomitant with the osteopenic syndrome is characterized by lipid shift towards pro-atherogenic fractions, reduced quality of life according to Seattle Angina Questionnaire, more frequent development of diastolic dysfunction, calcification of the heart valves and large vessels.

Conclusion. The correlation relationship with the T-score as the main parameter of the degree of the bone mineral density loss has been determined. 

References

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How to Cite

1.
Mykhailovskaya NS, Shevchenko IO, Nikituk OV. Clinical features of coronary heart disease in postmenopausal women, depending on the degree of bone mineral density loss. Current issues in pharmacy and medicine: science and practice [Internet]. 2015Jul.14 [cited 2024Dec.27];(2). Available from: http://pharmed.zsmu.edu.ua/article/view/45106

Issue

No. 2 (2015)

Section

Experimental and clinical pharmacology

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