Study of the chemical composition of the freon extract of the Damask rose (Rosa damascena Mill.)
DOI:
https://doi.org/10.14739/2409-2932.2023.1.269905Keywords:
Rosa damascena Mill., chromatography-mass spectrometry, chemical compositionAbstract
Rosa damascena Mill. a rather popular variety of roses has anti-inflammatory, wound-healing, and antiseptic effects.
The aim of this study was to establish the component composition of the freon extract of Damask rose grown in vitro and to substantiate the advantages of this method and the prospects for the use of phytosubstances in medical practice.
Materials and methods. The object of the study was the freon extract of Damask rose, grown by the method of clonal micropropagation in vitro. The qualitative and quantitative determination of the components of the freon extract was determined using the chromato-mass spectrometric method.
Results. According to the results of the chromato-mass-spectrometric study, 60 compounds were identified, 6 of which were in the isomeric state.
The following components prevailed by percentage: рhenylethyl alcohol – 64.070 %, citronellol – 6.090 %, nonadecane – 4.636 %, heneicosane – 2.590 %, geraniol – 1.749 %.
Conclusions. The chemical composition of the freon extract of Rosa damascena Mill., grown in vitro, was investigated for the first time using the chromato-mass-spectrometric method.
The main components of rose petals: рhenylethyl alcohol – 64.070 %, citronellol – 6.090 %, nonadecane – 4.636 %, heneicosane – 2.590 %, geraniol – 1.749 %.
References
Cairns, T., Young, M., Adams, J., & Edberg, B. (Eds.). (2000). Modern roses XI : the world encyclopedia of roses. Academic Press.
Griep, S. V. (2021, July 26). Heirloom Old Garden Rose Bushes: What Are Old Garden Roses?. Gardening Know How. https://www.gardeningknowhow.com/ornamental/flowers/roses/old-garden-roses.htm
Akram, M., Riaz, M., Munir, N., Akhter, N., Zafar, S., Jabeen, F., Ali Shariati, M., Akhtar, N., Riaz, Z., Altaf, S. H., Daniyal, M., Zahid, R., & Said Khan, F. (2020). Chemical constituents, experimental and clinical pharmacology of Rosa damascena: a literature review. The Journal of pharmacy and pharmacology, 72(2), 161-174. https://doi.org/10.1111/jphp.13185
Nayebi, N., Khalili, N., Kamalinejad, M., & Emtiazy, M. (2017). A systematic review of the efficacy and safety of Rosa damascena Mill. with an overview on its phytopharmacological properties. Complementary therapies in medicine, 34, 129-140. https://doi.org/10.1016/j.ctim.2017.08.014
Spasova Nunes, H., & Graça Miguel, M. (2017). Rosa damascena essential oils: a brief review about chemical composition and biological properties. Trends in Phytochemical Research (TPR) Trends Phytochem. Res (Vol. 1, pp. 111-128).
Davoodi, I., Rahimi, R., Abdollahi, M., Farzaei, F., Farzaei, M. H., Memariani, Z., & Najafi, F. (2017). Promising effect of Rosa damascena extract on high-fat diet-induced nonalcoholic fatty liver. Journal of traditional and complementary medicine, 7(4), 508-514. https://doi.org/10.1016/j.jtcme.2017.01.008
Rezvani-Kamran, A., Salehi, I., Shahidi, S., Zarei, M., Moradkhani, S., & Komaki, A. (2017). Effects of the hydroalcoholic extract of Rosa damascena on learning and memory in male rats consuming a high-fat diet. Pharmaceutical biology, 55(1), 2065-2073. https://doi.org/10.1080/13880209.2017.1362010
Hamdamian, S., Nazarpour, S., Simbar, M., Hajian, S., Mojab, F., & Talebi, A. (2018). Effects of aromatherapy with Rosa damascena on nulliparous women's pain and anxiety of labor during first stage of labor. Journal of integrative medicine, 16(2), 120-125. https://doi.org/10.1016/j.joim.2018.02.005
Mahboubi, M. (2015). Rosa damascena as holy ancient herb with novel applications. Journal of traditional and complementary medicine, 6(1), 10-16. https://doi.org/10.1016/j.jtcme.2015.09.005
Ghavam, M., Afzali, A., Manconi, M., Bacchetta, G., & Manca, M. L. (2021). Variability in chemical composition and antimicrobial activity of essential oil of Rosa × damascena Herrm. from mountainous regions of Iran. Chemical and Biological Technologies in Agriculture, 8(1). https://doi.org/10.1186/s40538-021-00219-6
State Enterprise Ukrainian Scientific Pharmacopoeial Center of Medicines Quality. (2015). Derzhavna Farmakopeya Ukrayiny [The State Pharmacopoeia of Ukraine (Vol. 1, 2nd ed.)]. Kharkiv: State Enterprise Ukrainian Scientific Pharmacopoeial Center of Medicines Quality. [in Ukrainian].
Odyntsova, V. M., Korniievska, V. H., Panchenko, S. V., Korniievskyi, Yu. I., & Kokitko, V. I. (2022). Khromato-mas-spektrometrychne doslidzhennia nastoiky valeriany z riznymy ekstrahentamy [Chromato-mass spectrometric study of valerian infusion with various extractants]. Current issues in pharmacy and medicine: science and practice, 15(1), 31-39. [in Ukrainian]. https://doi.org/10.14739/2409-2932.2022.1.252374
Eshkol, N., Sendovski, M., Bahalul, M., Katz-Ezov, T., Kashi, Y., & Fishman, A. (2009). Production of 2-phenylethanol from L-phenylalanine by a stress tolerant Saccharomyces cerevisiae strain. Journal of applied microbiology, 106(2), 534-542. https://doi.org/10.1111/j.1365-2672.2008.04023.x
Sharma, Y., Rastogi, S. K., Perwez, A., Rizvi, M. A., & Manzoor, N. (2020). β-citronellol alters cell surface properties of Candida albicans to influence pathogenicity related traits. Medical mycology, 58(1), 93-106. https://doi.org/10.1093/mmy/myz009
Lei, Y., Fu, P., Jun, X., & Cheng, P. (2019). Pharmacological Properties of Geraniol - A Review. Planta medica, 85(1), 48-55. https://doi.org/10.1055/a-0750-6907
Jirovetz, L., Buchbauer, G., Schmidt, E., Stoyanova, A. S., Denkova, Z., Nikolova, R., & Geissler, M. (2007). Purity, antimicrobial activities and olfactoric evaluations of geraniol/nerol and various of their derivatives. Journal of Essential Oil Research, 19(3), 288-291. https://doi.org/10.1080/10412905.2007.9699283
Hsouna, A. B., Trigui, M., Mansour, R. B., Jarraya, R. M., Damak, M., & Jaoua, S. (2011). Chemical composition, cytotoxicity effect and antimicrobial activity of Ceratonia siliqua essential oil with preservative effects against Listeria inoculated in minced beef meat. International journal of food microbiology, 148(1), 66-72. https://doi.org/10.1016/j.ijfoodmicro.2011.04.028
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