Study of the chemical composition of the freon extract of the Damask rose (Rosa damascena Mill.)

Authors

DOI:

https://doi.org/10.14739/2409-2932.2023.1.269905

Keywords:

Rosa damascena Mill., chromatography-mass spectrometry, chemical composition

Abstract

Rosa damascena Mill. a rather popular variety of roses has anti-inflammatory, wound-healing, and antiseptic effects.

The aim of this study was to establish the component composition of the freon extract of Damask rose grown in vitro and to substantiate the advantages of this method and the prospects for the use of phytosubstances in medical practice.

Materials and methods. The object of the study was the freon extract of Damask rose, grown by the method of clonal micropropagation in vitro. The qualitative and quantitative determination of the components of the freon extract was determined using the chromato-mass spectrometric method.

Results. According to the results of the chromato-mass-spectrometric study, 60 compounds were identified, 6 of which were in the isomeric state.

The following components prevailed by percentage: рhenylethyl alcohol – 64.070 %, citronellol – 6.090 %, nonadecane – 4.636 %, heneicosane – 2.590 %, geraniol – 1.749 %.

Conclusions. The chemical composition of the freon extract of Rosa damascena Mill., grown in vitro, was investigated for the first time using the chromato-mass-spectrometric method.

The main components of rose petals: рhenylethyl alcohol – 64.070 %, citronellol – 6.090 %, nonadecane – 4.636 %, heneicosane – 2.590 %, geraniol – 1.749 %.

Author Biographies

O. I. Panasenko, Zaporizhzhia State Medical University, Ukraine

PhD, Dsc, Professor, Head of the Department of Natural Sciences for Foreign Students and Toxicological Chemistry

V. M. Odyntsova, Zaporizhzhia State Medical University, Ukraine

PhD, Dsc, Professor of the Department of Pharmacognosy, Pharmacology and Botany

O. M. Denysenko, Zaporizhzhia State Medical University, Ukraine

PhD, Associate Professor of the Department of Pharmacognosy, Pharmacology and Botany

T. Ye. Shkopynska, Medical Professional College, Zaporizhzhia State Medical University, Ukraine

PhD

V. I. Mozul, Zaporizhzhia State Medical University, Ukraine

PhD, Associate Professor of the Department of Pharmacognosy, Pharmacology and Botany

V. V. Holovkin, Zaporizhzhia State Medical University, Ukraine

PhD, Associate Professor of the Department of Pharmacognosy, Pharmacology and Botany

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Published

2023-03-10

How to Cite

1.
Panasenko OI, Odyntsova VM, Denysenko OM, Shkopynska TY, Mozul VI, Holovkin VV. Study of the chemical composition of the freon extract of the Damask rose (Rosa damascena Mill.). Current issues in pharmacy and medicine: science and practice [Internet]. 2023Mar.10 [cited 2024Apr.14];16(1):18-22. Available from: http://pharmed.zsmu.edu.ua/article/view/269905

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Original research