Medical and geographical determinants of oncopathology in the population

Authors

DOI:

https://doi.org/10.14739/2409-2932.2021.3.239893

Keywords:

medical geography, oncopathology, irradiation

Abstract

The aim: to study the permanent risk factor of oncopathology in order to determine its medical and geographical features and assess their impact on oncopathology of the population of Zaporizhzhia region.

Materials and methods. By means of spatial and geographical, as well as analytical and statistical methods, territories were medically and statistically differentiated, with the assessment of the natural environment quality. Epidemiological study of malignant neoplasms was conducted retrospectively for the period of 2004–2015, in accordance with the International Classification of Diseases ICD-10. Determination of environmental impact on oncopathology was performed using the attributive fraction.

Results. Geoactive space is characterized by a variety of natural and climatic conditions of lithosphere, hydrosphere and landscapes. The main physical and geographical objects of the Zaporizhzhia region (Ukrainian Crystal Shield, the Dnipro, the Sea of Azov) form six zones, which differ in the diversity of system-forming elements. Specific features of discontinuous disturbances of the lithosphere of the Ukrainian crystal shield are abnormally high electrical conductivity of the earth’s crust, intense electromagnetic fields, high concentration of radon in aquifers, and streams of high-energy fluids.

Conclusions. The highest geopathogenic impact is manifested in the fault zone of the Ukrainian crystal shield. The highest values of the attributive fraction of malignant neoplasms were registered in this zone among the whole population (26.8 %), among the adult population (25.4 %) and the able-bodied population (32.7 %). The oncopathological potential of natural conditions was least manifested in the valley of the Dnipro breakthrough and the Azov Upland, where the attributive fraction for almost all indicators did not exceed 8.2 %.

Author Biographies

M. P. Hrebniak, Zaporizhzhia State Medical University, Ukraine

Dr.hab., Professor of the Department of General Hygiene and Ecology

O. V. Kirsanova, Zaporizhzhia State Medical University, Ukraine

PhD, Associate Professor of the Department of General Hygiene and Ecology

V. V. Taranov, Zaporizhzhia State Medical University, Ukraine

PhD, Associate Professor of the Department of Social Medicine, Public Health, Medical and Pharmaceutical Law

N. H. Mikriukova, Donetsk National Medical University, Mariupol, Ukraine

Senior Lecturer, Department of Higher Education, Health and Hygiene Management

References

Cherevatenko, A. A. (2018). Ekologicheskie faktory riska dlya zdorov'ya naseleniya [Environmental risk factors for public health]. Zhurnal fundamental'noi meditsiny i biologii, (3), 39-45. [in Russian].

Zaridze, D. G., Mukeriya, A. F., & Shan'gina, O. V. (2016). Vzaimodeistvie faktorov okruzhayushchei sredy i geneticheskogo polimorfizma v etiologii zlokachestvennykh opukholei [Interaction of environmental factors and genetic polymorphism in the etiology of cancer]. Uspekhi molekulyarnoi onkologii, 3(2), 8-17. [in Russian].

Hrebniak M. P., Kirsanova O. V., & Taranov V. V. (2020). Heopatohenni zony y onkolohichna zakhvoriuvanist naselennia [Geopathogenic zones and oncological morbidity of the population]. Zaporozhye medical journal, 22(6), 811-815. [in Ukrainian]. https://doi.org/10.14739/2310-1210.2020.6.218453

Solenova, L. G. (2020). Sovremennye podkhody k otsenke vliyaniya zagryazneniya okruzhayushchei sredy na onkologicheskii risk [Current approaches to assessment of the impact of the environmental contamination on cancer risk]. Uspekhi molekulyarnoi onkologii, 7(1), 17-22. [in Russian]. https://doi.org/10.17650/2313-805X-2020-7-1-17-22

Pavlenko, T. O. (2007). Rivni radonu u povitri budynkiv Ukrainy [Radon levels in the air of Ukrainian houses]. Dovkillia ta zdorovia, (2), 22-25. [in Ukrainian].

Antomonov, M. Yu. (2018). Matematicheskaya obrabotka i analiz mediko-biologicheskikh dannykh [Mathematical processing and analysis of biomedical data]. Medinform. [in Russian].

Alekhin, V. I., & Shagrova, A. A. (2009). Formy proyavleniya razlomnykh zon Priazovskogo geobloka USHCH v raznovozrastnykh kompleksakh porod i rudonosnost' [Manifestation forms of fault zones in the Priazovsky geoblock of the Ukrainian Shield in mixed age rock complexes and ore content]. Naukovi pratsi UkrNDMI NAN Ukrainy, (5, Pt 2), 305-315. [in Russian].

Burakhovich, T. K., Nikolaev, I. Yu., Sheremet, E. M., & Shirkov B. I. (2015). Geoelektricheskie anomalii Ukrainskogo shchita i ikh svyaz' s rudoproyavleniyami poleznykh iskopaemykh [Geoelectric anomalies of the Ukrainian shield and their relation to mineral deposits]. Geofizicheskii zhurnal, 37(6), 42-63. [in Russian].

Rybakov, Yu. L. (2013). Obshchee vozdeistvie na organizm slabogo nizkochastotnogo vikhrevogo magnitnogo polya pri razvitii opukholevogo protsessa (Avtoref. dis. ... kand. biol. nauk). [The general effect on the body of a weak low-frequency vortex magnetic field during the development of a tumor process] (Extended abstract of candidate’s thesis). Moscow. [in Russian].

Pavlenko, T. A., Kostenetsky, M. I., Kutsak, A. V., Sevalnev, A. I., Aksenov, N. V., & Fryziuk, M. A. (2013). Radon v doshkilnykh zakladakh Zaporizkoi oblasti ta dozy oprominennia ditei [Radon in preschool establishments in Zaporozhye region and doses of irradiation of children]. Environment & health, (1), 49-53. [in Ukrainian].

IARC Working Group on the Evaluation of Carcinogenic Risks to Humans. (2016). Outdoor air pollution. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, (No. 109). International Agency for Research on Cancer. https://www.ncbi.nlm.nih.gov/books/NBK368024/

IARS Working Group on the Evаluation of Carcinogenic Risks to Humans. (2012). Radiation. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, (No. 100D). International Agency for Research on Cancer. https://www.ncbi.nlm.nih.gov/books/NBK304362/

Ozerova, Yu. Yu., & Prylypko, V. A. (2020). Sotsialni ryzyky prozhyvannia poblyzu diiuchykh AES za rezultatamy sotsiolohichnoho doslidzhennia [Social risks of the residence next to existing NPP according to the results of a sociological survey]. Environment & health, (3), 40-47. [in Ukrainian]. https://doi.org/10.32402/dovkil2020.03.040

Kostenetskyi, M. I., Sevalniev, A. I., & Kutsak, A. V. (2019). Radon navkolo nas: problema ta shliakhy yii vyrishennia [Radon around us: the problem and ways to solve it]. Zaporіzhzhia: ZDMU. [in Ukrainian].

Korzun, V. N., Bolokhnova, T. V., Nester, T. I., & Parats, A. N. (2008). Problema mikroelementozov u naseleniya, podvergshegosya sochetannomu deistviyu radiatsionnogo i endemicheskogo faktorov [The problem of microelementosis in the population exposed to the combined action of radiation and endemic factors]. Zdorov'e i okruzhayushchaya sreda, 12, 149-156. [in Russian].

Rodgers, K. M., Udesky, J. O., Rudel, R. A., & Brody, J. G. (2018). Environmental chemicals and breast cancer: An updated review of epidemiological literature informed by biological mechanisms. Environmental research, 160, 152-182. https://doi.org/10.1016/j.envres.2017.08.045

Savel'eva, O. N. (2015). Psikhosomatika onkologicheskikh zabolevanii. Vestnik nauki i obrazovaniya [Psychosomatics of oncological diseases]. Vestnik nauki i obrazovaniya, (9), 75-76. [in Russian].

Ferlay J., Ervik M., Lam F., Colombet M., Mery L., Piñeros M., Znaor A., Soerjomataram I., & Bray F. (2020). Global Cancer Observatory: Cancer Today. Lyon, France: International Agency for Research on Cancer. Available from: https://gco.iarc.fr/today.

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Published

2021-10-25

How to Cite

1.
Hrebniak MP, Kirsanova OV, Taranov VV, Mikriukova NH. Medical and geographical determinants of oncopathology in the population. Current issues in pharmacy and medicine: science and practice [Internet]. 2021Oct.25 [cited 2024Nov.22];14(3):363-8. Available from: http://pharmed.zsmu.edu.ua/article/view/239893

Issue

Vol. 14 No. 3 (2021)

Section

Original research

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