Analysis of the current state and prospects for the development of sedatives in the modern Ukrainian pharmaceutical market
Keywords:pharmaceutical market, sedatives, assortment analysis, pharmaceutical preparations
Modern research has shown that cognitive impairments are directly related to behavioral disorders and psychopathological syndromes. Nootropic drugs used for pharmacotherapy of cognitive impairments demonstrate low clinical efficiency for the treatment of psychoemotional disorders. In this case, it is advisable to correct such states by prescribing sedatives that have an integrated effect on etiological factors, pathogenetic links and symptomatic manifestations of the disease.
The aim of the research was to carry out a comprehensive assortment analysis of sedative drugs within the pharmaceutical market of Ukraine.
Materials and methods. Studies were carried out through generally accepted statistical and marketing studies (State Register of Medicines of Ukraine, September, 2020). Our research focused on the information on the structure of the market of sedatives registered in Ukraine. Graphical and logical methods were used in the course of the study.
Results. The results of the study have shown that the products manufactured in the Ukrainian pharmaceutical enterprises take 71.50 % of this segment; whereas sedatives produced in Germany – 7.50 %; in Poland – 3.56 %; in Italy, Slovenia, France – 1.50 % for each respectively; in Austria, Malta, Great Britain – 1.02 % for each respectively. The preparations of this group are represented in solid (tablets, coated tablets, capsules, granules, herbs in packs and filter bags) and liquid (tinctures, drops, liquid extracts, elixirs, syrups, oral solutions) dosage forms. Among the studied medicines, solid dosage forms predominate; their share makes 62.7 % of the assortment, and the highest percentage rate is held by tablets (45.5 %). The largest market share of liquid medicinal forms is made by tinctures, in particular 18.9 %. The lowest percentage rates are observed in such medicinal forms as liquid extracts, drops, elixirs, syrups and oral solutions (15.5 % in general). Analysis of the state of the Ukrainian pharmaceutical market of sedatives shows that synthetic drugs account for 24.55 % of the market (tablets – 92.7 %), natural (plant) medicines – 75.45 % (solid dosage forms – 89.6 %).
Conclusions. Marketing studies were carried out on the modern market of sedative medicines in Ukraine. It has been established that the quantitative and qualitative diversity of the current assortment is presented by the imported drugs and domestic producers. Analysis of the state of the Ukrainian pharmaceutical market of sedatives was performed. Sedative preparations of natural (plant) origin have been found to be predominant and occupy 2/3 of the total range of sedatives registered in Ukraine as of September, 2020. Synthetic sedative drugs are mainly combined. Monodrugs of plant origin make up the majority of assorted items. Development of drugs aimed at providing complex pharmacotherapeutical correction of cognitive and psychoemotional disorders and based on such peptides as vasopressin, is one of the most significant and relevant problems in modern neurology and is of great scientific and practical value.
Maksymenko, K. S. (2016). Psikhologicheskaya spetsifika nepsikhoticheskikh lichnostnykh rasstroistv [Psychological specificity of non-psychotic personality disorders]. Problemy suchasnoi psikhologii, 31, 186-201. [in Russian].
Ostrovskiy D. I., & Ivanova T. I. (2020). Vliyanie novoi koronavirusnoi infektsii COVID-19 na psikhicheskoe zdorov'e cheloveka (obzor literatury) [Influence of the new coronovirus COVID-19 infection on human mental health (literature review)]. Omskii psikhiatricheskii zhurnal, 24(2-1S), 4-10. [in Russian]. https://doi.org/10.24411/2412-8805-2020-10201
Azimova, Yu. Ye, Ishchenko, K. A., Rachin, A. P. & Guseva, M. E. (2016). Depressiya i dementsiya: dve storony odnoi medali? [Depression and dementia: two sides of the same coin?]. Russkii meditsinskii zhurnal, 24(24), 1616-1619. [in Russian].
Burchinskii, S. G. (2015). Preparaty valeriany kak kompleksnye korrektory psikhoemotsional'nykh i kognitivnykh rasstroistv v nevrologii: novye vozmozhnosti [Valerian drugs as the comprehensive correctors of psycho-emotional and cognitive disorders in neurology: new opportunities]. Praktykuiuchyi likar, (3), 49-53. [in Russian].
Burchinskii, S. G. (2015). Novye podkhody k farmakoterapii i farmakoprofilaktike asteno-nevroticheskikh sostoyanii [New approaches to the pharmacotherapy and pharmacoprevention of asthenoneurotic states]. Praktykuiuchyi likar, (4), 45-48. [in Russian].
Rozhdestvenskii, D. A. (2015). Obzor klinicheskoi farmakologii sedativnukh sredstv [Review of clinical pharmacology of sedatives facilities]. Lechebnoe delo, (1), 13-21. [in Russian].
Kompendium. Likarski preparaty. [Compendium. Medicines]. http://compendium.com.ua
Derzhavnyi reiestr likarskykh zasobiv Ukrainy [State register of medicines of Ukraine]. http://www.drlz.kiev.ua
Grigoreva, L. M. & Piastolva, S. O. (2016). O ispolzovanii lekarstvennykh sredstv rastitelnogo proiskhozhdnia v psixiatii [About the use of medications of phytogenous in psychiatry]. Sovremennye tendentsii razvitiya nauki i tekhnologii, (1-3), 25-29. [in Russian].
Burchinskii, S. G. (2015). Depressivnye i distimicheskie rasstroistva pri psikhosomaticheskoi patologii i puti ikh farmakologicheskoi korrektsii [Depressive and dysthymic disorders in psychosomatic diseases and ways of their pharmacological correction]. Praktykuiuchyi likar, (2), 51-56. [in Russian].
Savelyeva, O. V. & Vladymyrova, I. M. (2015). Analiz nomenklatury sedativnykh ta snodiinykh preparativ v Ukraini [An analysis of nomenclature of sedative and somnolent drugs in Ukraine]. Farmatsevtychnyi chasopys, (3), 40-43. [in Ukrainian].
Mudrenko, I. G. (2017). Effektivnost kognifena v lechenii dementsii [Efficiency of kogniphen is in treatment of dementias]. Psikhiatriya, psikhoterapiya i klinicheskaya psikhologiya, 3(8), 324-336. [in Russian].
Gomazkov, O. A. Korteksin: molekulyarnye mekhanizmy i misheni neiroprotektivnoi aktivnosti [Cortexin: molecular mechanisms and targets of Neuropatronage activity]. Zhurnal nevrologii i psikhiatrii im. S. S. Korsakova, (8), 99-104. [in Russian].
Drozdov, A. L. (2015). Mnesticheskie effekty peptidov vazopressinovogo ryada [Mnestic effects of peptids of vazopressin row]. Dnepropetrovsk: Ekonomika. [in Russian].
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