Research of domestic market medicinal agents based on Minoxidil and it’s derivatives that are used in treatments for Alopecia

Authors

  • Zhamali Karim Zaporizhzhia State Medical University, Ukraine,
  • N. О. Tkachenko Zaporizhzhіa State Medical University, Ukraine,
  • V. V. Hladyshev Zaporizhzhia State Medical University, Ukraine,
  • S. Ye. Ryzhkova Zaporizhzhіa State Medical University, Ukraine,

DOI:

https://doi.org/10.14739/2409-2932.2019.3.184206

Keywords:

alopecia, aminexil, minoxidil, marketing

Abstract

 

The problem of development of the new domestic medicines for alopecia has been remained topical for some years. Marketing analysis of the mentioned segment always should be carried out at first. Today the pharmaceutical market is updating dynamically. This fact is causing the necessity of its investigation and formation of informational base concerning assortment dynamics, prices and accessibility of the pharmaceutical product at certain periods of its development.

The aim of this work is the formation of informational base of medicines and cosmetics for alopecia including minoxidil and its derivatives and substantiation based on marketing analysis of the feasibility of the creation new pharmaceutical product based on aminexil.

Materials and methods. The State Register of Medicines of Ukraine; the directory of medicines "Compendium online”; online resources for medicines search in Ukrainian pharmacies “GeoApteka” and “Tabletki.ua”; online resources of network pharmacies “Apteka nizkikh tsen” and “Med-service” were used as informational materials. The marketing method, methods of monitoring, logical generalization, grouping and graphical method were employed during the investigation.

Results. Complex marketing estimation of the Ukrainian pharmaceutical market of the medicines with minoxidil derivatives for alopecia including heterogeneous structure: medicines and cosmetics, was carried out. 

Conclusion. On the basis on the marketing analysis of the pharmaceutical market the modern arsenal of the medicines for the trichologists and pharmacists was compounded in two areas: segment “Medicines” included 4 medications of D11AX group “Other dermatological drugs”; segment “Cosmetics” included 29 products (mostly cosmetics with minoxidil – 17 positions).

As to form of manufacturing, liquid forms prevail in pharmacies, and there are shampoos and balsams. All medicines by the criterion “Procedure of dispensing in pharmacies” are OTC-products. The deficiency of aminexil based combined medicines and a small number of proposals from domestic producers are characteristic by the market analysis.

References

Kardashova, D. Z., Vasilenko, I. A.,  Karasev, E. A. (2012). Kompleksnyj podhod – osnova jeffektivnogo lechenija alopecii [Comprehensive approach is the basis for effective treament of alopecia]. Jeksperimentalnaja i klinicheskaja dermatokosmetologija, 1, 58-62. [in Russian].

Alopetsіia. [Alopecia]. Farmatsevtychna entsyklopediia. Retrieved from https://www.pharmencyclopedia.com.ua/article/2710/alopeciya [in Ukrainian].

Svjatenko, T. V.,  Andriuca, L. A. Alopecija: klassifikacii, jetiopatogenez, klinicheskie projavlenija, sovremennye vozmozhnosti terapii [Alopecia: classifications, pathogenesis, clinical features, current therapy options]. Retrieved from http://derma.dp.ua/literature/%D0%B0%D0%BB%D0%BE%D0%BF%D0%B5%D1%86%D0%B8%D1%8F-%D0%BA%D0%BB%D0%B0%D1%81%D1%81%D0%B8%D1%84%D0%B8%D0%BA%D0%B0%D1%86%D0%B8%D0%B8-%D1%8D%D1%82%D0%B8%D0%BE%D0%BF%D0%B0%D1%82%D0%BE%D0%B3%D0%B5%D0%BD/ [in Russian].

Yurlova, L. V. (2008). Dyferentsіiovana terapіia hnіzdovoi alopetsіi z urakhuvanniam klіnіko-patohenetychnykh osoblyvostei zakhvoriuvannia [The differentiated therapy of alopecia areata when considering the clinical-pathogenetic features of the disease]. Ukrainskyi zhurnal dermatolohii, venerolohii, kosmetolohii, 3, 41-45. [in Ukrainian].

Fedorovska, M. I., Polovko, N. P.,  Yarema, I. O. (2018). Metodolohіia stvorennia dermatokosmetychnykh zasobіv dlia profіlaktyky ta lіkuvannia alopetsіi [The methodology of developing dermato-cosmetic remedies for prevention and treatment of alopecia]. Clinical pharmacy, 22(1), 20-27. doi: https://doi.org/10.24959/cphj.18.1450 [in Ukrainian].

Pavkh, O. I., Sokolova, L. V., Kozyr, G. R.,  Barna, A. M. (2012). Rozrobka skladu lіkuvalno-kosmetychnoho zasobu dlia profіlaktyky vypadіnnia volossia [Formulation development of medical and cosmetic products for preventing hair loss]. Zaporozhye medical journal, 3, 26–27. [in Ukrainian].

Fedorovska, M. I. (2014). Perspektyvy zastosuvannia lіkarskykh roslyn pry rіznykh formakh alopetsіi [Prospect of medicinal plants application in various forms of alopecia]. Fіtoterapіia. Chasopys, 2, 40-44. [in Ukrainian].

Demchuk, M. B., Ivashkiv, Yu. I.,  Hroshovuy, T. A. (2012). Doslіdzhennia vіtchyznianoho rynku lіkarskykh preparatіv і zasobіv lіkuvalnoi kosmetyky, shho vykorystovuiutsia pry zovnіshnіi korektsіi alopetsіi [The domestic market analysis of medicines and medical cosmetics used for external correction of alopecia]. Zaporozhye medical journal, 3, 23-25. [in Ukrainian].

Yarema, I. O., Fedorovska, M. I.,  Sokolova, L. V. (2014). Marketynhovі doslіdzhennia rynku lіkarskykh і kosmetychnykh zasobіv, shho pryznachenі dlia zastosuvannia pry rіznykh formakh alopetsіi [Marketing researches of medicinal and cosmetic remedies intended for applying in various forms of alopecia]. Current issues in pharmacy and medicine: science and practice, 3, 106-110. [in Ukrainian].

Analogi minoksidila. Chast 2 [Minoxidil analogues. Part 2]. Retrieved from http://mayya.ucoz.com/blog/analogi_minoksidila_chast_2/2013-10-19-42 [in Russian].

Kompendium. Lekarstvennye preparaty. [Compendium. Medicines]. Retrieve from http://compendium.com.ua. [in Russian].

Derzhavnyi reiestr likarskykh zasobiv Ukrainy [State register of medicines of Ukraine]. Retrieve from http://www.drlz.kiev.ua [in Ukrainian].

Downloads

How to Cite

1.
Karim Z, Tkachenko NО, Hladyshev VV, Ryzhkova SY. Research of domestic market medicinal agents based on Minoxidil and it’s derivatives that are used in treatments for Alopecia. Current issues in pharmacy and medicine: science and practice [Internet]. 2019Nov.21 [cited 2024Apr.25];(3). Available from: http://pharmed.zsmu.edu.ua/article/view/184206

Issue

No. 3 (2019)

Section

Original research

License

Authors who publish with this journal agree to the following terms:

    1. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.     Лицензия Creative Commons
    2. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
    3. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access)