Clinical and electroencephalographic correlations in patients with cerebral ischemic hemispheric stroke in early recovery period of disease

Authors

  • S. O. Medvedkova Zaporizhzhіa State Medical University, Ukraine,

DOI:

https://doi.org/10.14739/2409-2932.2018.1.123642

Keywords:

cerebral infarction, electroencephalography, prognosis

Abstract

The aim is to investigate the state of bioelectric activity of the brain in comparison with clinical neurological data in patients with cerebral ischemic hemispheric stroke (CIHS) in the early recovery period of the disease.

Materials and methods: complex clinical and instrumental research was done in 60 patients (23 men and 37 women, age 58 (54; 66) years) with cerebral ischemic hemispheric stroke in early recovery period of disease, which included the indication according to the stroke scale of National Institute of Health (NIHSS) and modified Rankin Scale on the 10th, 30th, 90th and 180th day of disease. To evaluate the functional state of the brain on the 10th day of CIHS, computer electroencephalography was performed with the determination of the parameters as for spectral analysis of the bioelectric activity of the brain.

Results. It was defined that with the level of disability on the 180 day of CIHS most closely related to each other the value of the relative spectral power (RSP) rhythms δ-subrange of affected hemisphere (AH) (R = +0.41, P < 0.05), RSP rhythms δ-subrange of intact hemisphere (IH) (R = + 0.43, P < 0.05), RSP rhythms θ1-subrange of AH (R = + 0.42, P < 0.05), RSP rhythms θ1-subrange of IH (R = +0.46, P < 0.05), RSP rhythms θ2subrange of AH (R = +0.38, P < 0.05), RSP rhythms θ2-subrange of IH (R = +0.42, P < 0.05), RSP rhythms θ-subrange of AH (R = +0.41, P < 0.05), RSP rhythms θ-subrange of IH (R = +0.43, P < 0.05),  and also integral coefficients DAR AH (R = +0.41, P < 0.05), DAR IH (R = +0.45, P < 0.05), DTABR AH (R = +0.52, P < 0.05), DTABR IH (R = + 0.51, P < 0.05), TAR AH (R = +0.41, P < 0.05) and TAR IH  (R = +0.41, P < 0.05).

Conclusion. The level of disability on the 180th day of CIHS is correlated with the values of DTABR of the affected (R = +0.52, P < 0.05) and intact hemisphere (R = + 0.51, P < 0.05) on the 10th day of the disease.

References

Kuznietsov, A. А. (2013) Kliniko-elektroentsefalohrafo-hemodynamichni zistavlennia u khvorykh pid chas hostroho ishemichnoho supratentorialnoho insultu [Сlinical, electroencephalographic and cerebral hemodynamic comparisons in patients with ischemic supratentorial stroke in acute period]. Pathologia, 2(28), 62–67. [in Ukrainian].

Mishchenko, T. S. (2017) Epidemiolohiia tserebrovaskuliarnykh zakhvoriuvan i orhanizatsiia dopomohy khvorym z mozkovym insultom v Ukraini [Epidemiology of cerebrovascular diseases and organization of medical care for patients with stroke in Ukraine]. Ukrainskyi visnyk psykhonevrolohii, 25, 1(90), 22–24. [in Ukrainian].

Pohorielov, O. V. (2012) Kliniko-neirofiziolohichni osoblyvosti perebihu hostrykh ishemichnykh porushen mozkovoho krovoobihu (Dis… dokt. med. nauk). [Clinical and neurophysiological features of the course of acute ischemic violations of cerebral circulation. Dr. med. sci. diss.]. Dnipropetrovsk. [in Ukrainian].

Polue'ktov, M. G., & Centeradze, S. L. (2015) Dopolnitel'nye vozmozhnosti vosstanovleniya bol'nykh, perenesshikh ishemicheskij insul't [Additional possibilities of restoration of patients who have suffered an ischemic stroke]. E'ffektivnaya farmakoterapiya, 13, 20–26. [in Russian].

Stasenko, T. (2017) Insult: vprovadzhennia uspishnykh stratehii likuvannia [Stroke: Implementation of successful treatment strategies]. Ukrainskyi medychnyi chasopys. Retrieved from http://www.umj.com.ua/article/117650/insult-vprovadzhennya-uspishnih-strategij-likuvannya. [in Ukrainian].

Tanashyan, M. M., Maksimova, M. Yu., Domashenko, M. A., & Raskurazhev, A. A. (2015) Vtorichnaya profilaktika cerebrovaskulyarnykh zabolevanij [Secondary prevention of cerebrovascular diseases]. Akademiya insul'ta, 3, 78–132. [in Russian].

Chernij, E. V. (2009) Bioe'lektricheskaya aktivnost' mozga pri ostrykh narusheniyakh mozgovogo krovoobrashcheniya v usloviyakh farmakologicheskoj blokady kal'ciyevykh kanalov (Dis… kand. med. nauk). [Bioelectric activity of the brain with acute cerebrovascular disorders in the conditions of the pharmacological blockade of calcium channels Dr. med. sci. diss.]. Doneck. [in Russian].

Chystik, T. (2016) Mezhdunarodnyj proe'kt eso-east v Ukraine: optimizaciya i uluchsheniye kachestva pomoshchi paciyentam s insul'tom [International project eso-east in Ukraine: optimization and improvement of quality of care for patients with a stroke]. Mezhdunarodnyj nevrologicheskij zhurnal, 7(85), 56–59 [in Russian]. doi: 10.22141/2224-0713.7.85.2016.86918.

Finnigan, S., & van Putten, M. J. (2013) EEG in ischemic stroke: quantitative EEG can uniquely inform (sub-) acute prognoses and clinical management. Clinical Neurophysiology, 124, 10–19. doi: 10.1016/j.clinph.2012.07.003.

Jordan, K. G. (2004) Emergency EEG and continuous EEG monitoring in acute ischemic stroke. Journal of Clinical Neurophysiology, 21(5), 341–352.

Phan, T. G., Chen, J., Donnan, G., Srikanth, V., Wood, A., & Reutens, D. C. (2010) Development of a new tool to correlate stroke outcome with infarct topography: a proof-of-concept study. Neuroimage, 49(1), 127–133. doi: 10.1016/j.neuroimage.2009.07.067.

Downloads

How to Cite

1.
Medvedkova SO. Clinical and electroencephalographic correlations in patients with cerebral ischemic hemispheric stroke in early recovery period of disease. CIPM [Internet]. 2018Feb.16 [cited 2023Dec.9];(1). Available from: http://pharmed.zsmu.edu.ua/article/view/123642

Issue

No. 1 (2018)

Section

Experimental and clinical pharmacology

License

Authors who publish with this journal agree to the following terms:

    1. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.     Лицензия Creative Commons
    2. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
    3. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access)