Analysis of pharmaceutical market of dietary supplements with green tea leaves extract

Results. The assortment of dietary supplements with green tea leaves extract has been analyzed. The results showed that the leaders in the number of manufacturers in the analyzed group of dietary supplements are the United States, Ukraine, and Poland, their part is 61 %, 16 % and 8 %, respectively. In terms of assortment, the United States ranks first – 66 %. Dietary supplements are presented in 6 dosage forms, most of them are capsules (60 %). It was determined that monopreparations predominate in the pharmaceutical market and account for 77 %. The price segmentation of the market of dietary supplements with green tea leaves extract has been provided, the results showed that most of these are dietary supplements in the price range of 200–500 UAH. The study of the company structure made it possible to identify leaders among foreign companies; the top three companies included Now Foods (27 %), Swanson (20 %), Puritan’s Pride (14 %).

Approximately 70 % of US adults use dietary supplements [3]. In Europe, the leaders in the consumption of dietary supplements are Italy, Russia, Germany, Great Britain and France. The Ukrainian market of dietary supplements in monetary terms in 2015 was estimated at 75.7 million euros with a tendency to reach 87.1 million euros in 2020 [4]. Today, there is a stable growth dynamics in demand and supply of dietary supplements with antioxidant activity [5]. The global antioxidants market size was valued at $3,437.3 million in 2020, and is projected to reach $7,376.4 million by 2031 [6]. Vitamins A, E, C are expected to have the highest sales among antioxidants, but this is more likely due to their vitamin properties than antioxidant ones. Among the drugs better known for their antioxidant properties, resveratrol, precursors of glutathione, selenium, carotenoids, coenzyme Q concentrates, and green tea extracts have the highest sales volumes [7].
Today, there are no green tea-based medicines in Ukrainian pharmacies, which, in our opinion, is due to the perception of green tea more as a food type than a medicine. However, the pharmaceutical market has a wide choice of dietary supplements with green tea that is used as antioxidants.

Aim
The aim was to study the assortment of dietary supplements with green tea leaves extract on the modern pharmaceutical market to further search for ways to improve and optimize pharmaceutical supply.

Materials and methods
The object of the study was information about dietary supplements with green tea leaves extract on pharmaceutical market of Ukraine. The assortment of dietary supplements with green tea leaves extract was studied basing on the search of dietary supplements in pharmacies of Ukraine in the internet resources. For study of assortment of dietary supplements, the following methods were used: marketing, statistical, logic and graphic.

Results
According to obtained results as shown in Table 1, there are 42 dietary supplements with green tea leaves extract at the beginning of 2022 in Ukraine.
Today, there are 16 % of Ukrainian and 84 % of foreign dietary supplements on Ukrainian pharmaceutical market of dietary supplements with green tea leaves extract (Fig. 1).
In addition, a part of mono-and combined preparations, equal 24 and 77 %, respectively, was established (Fig. 2). According to the results of the study, it is obvious that the number of monopreparations is greater than that of the combined ones, which in turn is associated with the difficulties of technological production and the complexity of standardizing combined drugs.
According to the results, it has been determined that the first position in the ranking of country-manufacturer by the number of companies is the USA with 61 %. The second position belongs to Ukraine -16 %, and the third -to Poland (8 %). Analysis of the rating of country-manufacturer on the range of dietary supplements with green tea leaves extract by the number of assortment has showed that the first position is occupied by the USA (66 %), the second one belongs to Ukraine (15 %), and the third one -to Poland (6 %) ( Table 2). The analysis of pharmaceutical manufacturers has provided an assessment of 6 leading positions in the range of dietary supplements in this group. The following leaders have been identified: NOW Foods -31 %, Swanson -23 %, Purtan`s Pride (13 %), Klaine Labs (13 %), Source Natural (13 %), Elit-pharm (13 %) (Fig. 3).
Price, along with the effectiveness, is an important criterion for choosing a dietary supplement. Thus, a price segmentation of the market of dietary supplements with green tea leaves extract has been provided, which allowed to identify 4 groups of dietary supplements in the study group by their value. According to the results, the share of dietary supplements priced up to 200 UAH is 28 %; drugs priced between 200 and 500 UAH account for 42 %. The price range from 500 to 800 UAH includes 22 % of supplements, and supplements priced over 800 UAH make 10 % (Fig. 4).
The minimum retail price for dietary supplements with green tea leaves extract is set at Green Tea Extract (Nosorog, USA) -95 UAH, the second position is taken by Green Tea (Novofit, Ukraine) -75 UAH. The maximum price is for dietary supplements of foreign manufacture "Advanced Inflammation" (Klaire Labs, USA) -1886 UAH. (Table 1) Features of introduction into the body and dosage form help manufacturers most successfully solve the issues of con-     A study of this market segment by dosage form indicated the heterogeneity of dietary supplements. Thus, the analyzed group of dietary supplements was represented by 6 dosage forms such as capsules, tablets, drops, gels, teas, powders. The most widespread dosage form is capsules (60 %), followed by tablets (28 %) and the smallest share belongs to drops, teas, gels and powders, with each equal to 2 % (Fig. 5).

Discussions
The number of dietary supplements, as of 2022, compared to 2015 has increased [8]. 2. According to the results of marketing research on the temporary pharmaceutical market of Ukraine, 84 % of dietary supplements with green tea lextract are presented by foreign manufacturers, mainly by monopreparations, in the form of capsules and in the price range from 200 to 500 UAH.
3. As the pharmaceutical market of Ukraine is dominated by foreign dietary supplements with green tea leaves extract, the results of the analysis of the assortment confirm the relevance of developing a new Ukrainian dietary supplements that could be used as antioxidants.
Prospects for further research. The results of the analysis indicate to further search for ways to improve and optimize pharmaceutical supply.  Fig. 4. Diagram of distribution of dietary supplements with green tea leaves extract by price (%).